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Z-L-Phe chloromethyl ketone

CAS 26049-94-5 · Ketone · 3 functional traits · cGMP compliant · Ships from USA in 2-3 days

Ketone

Z-L-Phe chloromethyl ketone

Halogenated PharmaceuticalFine ChemicalAgrochemicalResearchChemical ManufacturingMedicinal Chemistry
CAS Number 26049-94-5
Category Ketone · Chlorinated Compound
Origin USA
Compliance cGMP

Questions? Contact our chemistry team:

chemistry@chem-contract.com | +1 (714) 732-8549
In stock — typically ships within 2-3 business days

About Z-L-Phe chloromethyl ketone

Z-L-Phe chloromethyl ketone (CAS Number: 26049-94-5) is a ketone-containing compound with a carbonyl center flanked by carbon substituents with defined stereochemistry. ChemContract Research supplies this moderate-complexity compound in high purity from our Huntington Beach, California facility, ensuring consistent quality and reliable domestic delivery throughout the United States.

Ketones serve as strategic intermediates in retrosynthetic planning — their carbonyl can be disconnected in multiple directions, providing flexible synthetic access to complex targets. Chloro substituents serve a dual role in drug design — as synthetic handles for late-stage functionalization and as bioisosteres that modulate lipophilicity and binding affinity. Chirality matters profoundly in drug action — enantiomers can differ by orders of magnitude in potency, and FDA guidelines increasingly require single-enantiomer development.

Primary applications include asymmetric reduction to chiral alcohols using cbs or noyori catalysts and nucleophilic aromatic substitution (snar) for ether and amine formation. This compound serves researchers and manufacturers across the pharmaceutical, fine chemical, agrochemical sectors. Whether you require Z-L-Phe chloromethyl ketone for early-stage research, process development, or commercial-scale production, ChemContract Research offers flexible ordering from milligram to multi-kilogram quantities with custom synthesis options and full batch documentation including Certificates of Analysis (CoA) and Safety Data Sheets.

Functional Groups: Ketone (C=O)Chlorine (C–Cl)
Stereochemistry: Defined Configuration

Ketone Applications & Target Industries

How Z-L-Phe chloromethyl ketone is used across pharmaceutical and fine chemical sectors

01

Asymmetric reduction to chiral alcohols using CBS or Noyori catalysts

02

Nucleophilic aromatic substitution (SNAr) for ether and amine formation

03

Enantiopure building block for single-enantiomer drug development

04

Grignard and organolithium additions for tertiary alcohol synthesis

05

Grignard reagent precursor for C–C bond construction

06

Chiral resolution standard or chiral HPLC reference compound

Target Industries: PharmaceuticalFine ChemicalAgrochemicalResearchChemical ManufacturingMedicinal Chemistry

Z-L-Phe chloromethyl ketone Specifications

Detailed specifications for this ketone, including purity, molecular weight, and analytical data are available upon request. Every batch from ChemContract Research includes:

  • Certificate of Analysis (CoA) with purity verification
  • HPLC, NMR, and/or mass spectrometry characterization data
  • Material Safety Data Sheet (MSDS/SDS)
  • Batch-specific documentation and lot traceability
  • Custom analytical testing available on request
Request Full Specifications

Quick Reference

Compound Name Z-L-Phe chloromethyl ketone
Type Ketone
Category Ketone · Chlorinated Compound
Purity ≥95% (custom grades available)
Stereochemistry Defined configuration (chiral HPLC verified)
Complexity Moderate (2 functional groups, 0 rings)
Compliance cGMP
Packaging mg to kg scale

Storage & Handling for Ketones

Handling Guidelines

Handle with standard laboratory precautions. Some ketones are flammable. Use adequate ventilation and wear safety glasses and gloves. Some chlorinated compounds are volatile or irritating. Use a fume hood and appropriate PPE. Acid chlorides react vigorously with water. Handle with standard precautions. Ensure proper labeling of stereochemical identity to prevent mix-ups.

Storage Conditions

Store at room temperature in a tightly sealed container. Protect from direct sunlight and heat sources. Store at recommended temperature in a well-sealed container. Protect from moisture and strong bases. Store under recommended conditions. Some chiral compounds may racemize at elevated temperatures or in the presence of base.

Why Buy Z-L-Phe chloromethyl ketone From ChemContract?

Quality Assured

Every batch of Z-L-Phe chloromethyl ketone is produced under cGMP conditions with full CoA documentation, HPLC purity verification, and lot traceability.

Fast USA Shipping

Ship from our Huntington Beach, CA facility with 2-3 business day domestic delivery. No import delays, no customs fees, no tariff surprises.

Custom Synthesis

Need a specific grade, quantity, or derivative of Z-L-Phe chloromethyl ketone? Our team of PhD chemists can develop custom synthesis solutions for your exact requirements.

Frequently Asked

Common questions about Z-L-Phe chloromethyl ketone

What is Z-L-Phe chloromethyl ketone used for? +

Z-L-Phe chloromethyl ketone is a ketone-containing compound with a carbonyl center flanked by carbon substituents used primarily in the pharmaceutical and fine chemical industries. Key applications include asymmetric reduction to chiral alcohols using cbs or noyori catalysts and nucleophilic aromatic substitution (snar) for ether and amine formation.

Where can I buy Z-L-Phe chloromethyl ketone in the USA? +

ChemContract Research is a trusted USA-based supplier of Z-L-Phe chloromethyl ketone. We offer competitive pricing, fast domestic shipping from our Huntington Beach, California facility, and full quality documentation including Certificates of Analysis (CoA). Request a quote at chemistry@chem-contract.com or call +1 (714) 732-8549.

What purity levels are available for Z-L-Phe chloromethyl ketone? +

ChemContract Research supplies Z-L-Phe chloromethyl ketone in multiple purity grades: ≥95% standard grade, ≥97% high-purity grade, and ≥99% ultra-high-purity grade depending on application requirements. We can also provide custom purity grades through our synthesis capabilities. Contact us for specific purity information and CoA documentation.

Can ChemContract synthesize Z-L-Phe chloromethyl ketone in custom quantities? +

Yes. ChemContract Research offers custom synthesis services for Z-L-Phe chloromethyl ketone from milligram to multi-kilogram scale. Our cGMP-compliant facilities and experienced chemists can accommodate custom specifications, packaging requirements, and delivery timelines. Contact our team to discuss your project.

What coupling reactions can I run with Z-L-Phe chloromethyl ketone? +

As a chlorinated compound, Z-L-Phe chloromethyl ketone is an excellent substrate for palladium-catalyzed cross-coupling reactions including Suzuki, Heck, Negishi, Sonogashira, and Buchwald–Hartwig amination. It can also be used for Grignard reagent preparation, metal–halogen exchange with organolithium reagents, and nucleophilic substitution reactions.

What is the stereochemical purity of Z-L-Phe chloromethyl ketone? +

ChemContract Research supplies Z-L-Phe chloromethyl ketone with verified enantiomeric or diastereomeric purity as documented in our Certificate of Analysis (CoA). Chiral HPLC analysis is standard for stereodefined compounds. We can provide material with ≥98% ee/de for demanding applications. Contact us for specific optical purity requirements.

How should I store Z-L-Phe chloromethyl ketone? +

Store at room temperature in a tightly sealed container. Protect from direct sunlight and heat sources. Store at recommended temperature in a well-sealed container. Protect from moisture and strong bases. Store under recommended conditions. Some chiral compounds may racemize at elevated temperatures or in the presence of base. Always consult the compound-specific Safety Data Sheet (SDS) provided with your order for detailed storage requirements. ChemContract Research includes handling and storage documentation with every shipment.

What is the CAS number of Z-L-Phe chloromethyl ketone? +

The CAS Registry Number for Z-L-Phe chloromethyl ketone is 26049-94-5. This unique identifier is used worldwide to reference this specific compound in chemical databases, regulatory filings, and scientific literature. ChemContract Research supplies this compound with full quality documentation. Contact us at chemistry@chem-contract.com for availability and pricing.

Chemical analysis laboratory with HPLC instruments for purity and impurity testing Custom chemical synthesis reaction setup for pharmaceutical intermediate production

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