Frequently Asked
Common questions about tert-butyldimethylsilyl trifluoromethanesulfonate
What is tert-butyldimethylsilyl trifluoromethanesulfonate used for?
tert-butyldimethylsilyl trifluoromethanesulfonate is a sulfur-functionalized compound with diverse reactivity used primarily in the pharmaceutical and medicinal chemistry industries. Key applications include sulfonamide pharmacophore installation for antibiotic and diuretic development and metabolic blocking strategy — fluorine substitution to improve drug half-life.
Where can I buy tert-butyldimethylsilyl trifluoromethanesulfonate in the USA?
ChemContract Research is a trusted USA-based supplier of tert-butyldimethylsilyl trifluoromethanesulfonate. We offer competitive pricing, fast domestic shipping from our Huntington Beach, California facility, and full quality documentation including Certificates of Analysis (CoA). Request a quote at chemistry@chem-contract.com or call +1 (714) 732-8549.
What purity levels are available for tert-butyldimethylsilyl trifluoromethanesulfonate?
ChemContract Research supplies tert-butyldimethylsilyl trifluoromethanesulfonate in multiple purity grades: ≥95% standard grade, ≥97% high-purity grade, and ≥99% ultra-high-purity grade depending on application requirements. We can also provide custom purity grades through our synthesis capabilities. Contact us for specific purity information and CoA documentation.
Can ChemContract synthesize tert-butyldimethylsilyl trifluoromethanesulfonate in custom quantities?
Yes. ChemContract Research offers custom synthesis services for tert-butyldimethylsilyl trifluoromethanesulfonate from milligram to multi-kilogram scale. Our cGMP-compliant facilities and experienced chemists can accommodate custom specifications, packaging requirements, and delivery timelines. Contact our team to discuss your project.
Why is fluorine important in tert-butyldimethylsilyl trifluoromethanesulfonate?
The fluorine atom(s) in tert-butyldimethylsilyl trifluoromethanesulfonate confer several advantages in drug design: increased metabolic stability due to the strong C–F bond (485 kJ/mol), enhanced lipophilicity for improved membrane permeability, and potential for favorable electrostatic interactions with biological targets. These properties make fluorinated compounds like tert-butyldimethylsilyl trifluoromethanesulfonate valuable in pharmaceutical development.
How should I store tert-butyldimethylsilyl trifluoromethanesulfonate?
Store in a cool, dry place in a tightly sealed container. Protect from moisture and light as specified. Store at recommended temperature in a tightly sealed container. Protect from moisture, heat, and incompatible materials. Store under inert atmosphere in a dry, cool place. Protect from moisture and air. Always consult the compound-specific Safety Data Sheet (SDS) provided with your order for detailed storage requirements. ChemContract Research includes handling and storage documentation with every shipment.
What is the CAS number of tert-butyldimethylsilyl trifluoromethanesulfonate?
The CAS Registry Number for tert-butyldimethylsilyl trifluoromethanesulfonate is 69739-34-0. This unique identifier is used worldwide to reference this specific compound in chemical databases, regulatory filings, and scientific literature. ChemContract Research supplies this compound with full quality documentation. Contact us at chemistry@chem-contract.com for availability and pricing.
