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(S)-Boc-5-oxopyrrolidine-2-carboxylic acid  97%

CAS 53100-44-0 · Boc-Protected · 3 functional traits · cGMP compliant · Ships from USA in 2-3 days

Boc-Protected

(S)-Boc-5-oxopyrrolidine-2-carboxylic acid  97%

Boc-Protected PharmaceuticalPeptide SynthesisFine ChemicalBiotechPolymerAgrochemical
CAS Number 53100-44-0
Category Boc-Protected · Carboxylic Acid
Origin USA
Compliance cGMP

Questions? Contact our chemistry team:

chemistry@chem-contract.com | +1 (714) 732-8549
In stock — typically ships within 2-3 business days

About (S)-Boc-5-oxopyrrolidine-2-carboxylic acid  97%

(S)-Boc-5-oxopyrrolidine-2-carboxylic acid  97% (CAS Number: 53100-44-0) is a Boc (tert-butyloxycarbonyl)-protected amino compound for orthogonal synthesis featuring a Pyrrolidine ring with defined stereochemistry. ChemContract Research supplies this moderate-complexity compound in high purity from our Huntington Beach, California facility, ensuring consistent quality and reliable domestic delivery throughout the United States.

The Boc group is removed cleanly with TFA or HCl in dioxane, making it orthogonal to Fmoc, Cbz, and Alloc protecting groups — essential for synthesizing complex peptide therapeutics. Carboxylic acids are among the most synthetically versatile functional groups — they can be converted to amides, esters, acid chlorides, anhydrides, alcohols, and aldehydes in a single step. Chirality matters profoundly in drug action — enantiomers can differ by orders of magnitude in potency, and FDA guidelines increasingly require single-enantiomer development.

Primary applications include solid-phase peptide synthesis (spps) with orthogonal boc/fmoc strategies and amide bond formation via edc/hobt or hatu coupling in peptide synthesis. This compound serves researchers and manufacturers across the pharmaceutical, peptide synthesis, fine chemical sectors. Whether you require (S)-Boc-5-oxopyrrolidine-2-carboxylic acid  97% for early-stage research, process development, or commercial-scale production, ChemContract Research offers flexible ordering from milligram to multi-kilogram quantities with custom synthesis options and full batch documentation including Certificates of Analysis (CoA) and Safety Data Sheets.

Ring Systems: Pyrrolidine
Functional Groups: Carboxylic acid (–COOH)Boc protecting group
Stereochemistry: Defined Configuration

Boc-Protected Applications & Target Industries

How (S)-Boc-5-oxopyrrolidine-2-carboxylic acid  97% is used across pharmaceutical and peptide synthesis sectors

01

Solid-phase peptide synthesis (SPPS) with orthogonal Boc/Fmoc strategies

02

Amide bond formation via EDC/HOBt or HATU coupling in peptide synthesis

03

Enantiopure building block for single-enantiomer drug development

04

Multi-step pharmaceutical synthesis requiring selective amine deprotection

05

Salt formation with amines to improve drug crystallinity and stability

06

Chiral resolution standard or chiral HPLC reference compound

Target Industries: PharmaceuticalPeptide SynthesisFine ChemicalBiotechPolymerAgrochemical

(S)-Boc-5-oxopyrrolidine-2-carboxylic acid  97% Specifications

Detailed specifications for this boc-protected, including purity, molecular weight, and analytical data are available upon request. Every batch from ChemContract Research includes:

  • Certificate of Analysis (CoA) with purity verification
  • HPLC, NMR, and/or mass spectrometry characterization data
  • Material Safety Data Sheet (MSDS/SDS)
  • Batch-specific documentation and lot traceability
  • Custom analytical testing available on request
Request Full Specifications

Quick Reference

Compound Name (S)-Boc-5-oxopyrrolidine-2-carboxylic acid  97%
Type Boc-Protected
Category Boc-Protected · Carboxylic Acid
Purity ≥95% (custom grades available)
Stereochemistry Defined configuration (chiral HPLC verified)
Complexity Moderate (2 functional groups, 1 ring)
Compliance cGMP
Packaging mg to kg scale

Storage & Handling for Boc-Protecteds

Handling Guidelines

Boc-protected compounds are generally stable. TFA deprotection generates isobutylene gas — perform in a fume hood. Acids may be corrosive or irritating. Handle with chemical-resistant gloves and eye protection. Use a fume hood for volatile acids. Handle with standard precautions. Ensure proper labeling of stereochemical identity to prevent mix-ups.

Storage Conditions

Store at room temperature in a sealed container. Stable under neutral and basic conditions; avoid strong acids during storage. Store at room temperature in a tightly sealed container. Protect from moisture and strong bases. Store under recommended conditions. Some chiral compounds may racemize at elevated temperatures or in the presence of base.

Why Buy (S)-Boc-5-oxopyrrolidine-2-carboxylic acid  97% From ChemContract?

Quality Assured

Every batch of (S)-Boc-5-oxopyrrolidine-2-carboxylic acid  97% is produced under cGMP conditions with full CoA documentation, HPLC purity verification, and lot traceability.

Fast USA Shipping

Ship from our Huntington Beach, CA facility with 2-3 business day domestic delivery. No import delays, no customs fees, no tariff surprises.

Custom Synthesis

Need a specific grade, quantity, or derivative of (S)-Boc-5-oxopyrrolidine-2-carboxylic acid  97%? Our team of PhD chemists can develop custom synthesis solutions for your exact requirements.

Frequently Asked

Common questions about (S)-Boc-5-oxopyrrolidine-2-carboxylic acid  97%

What is (S)-Boc-5-oxopyrrolidine-2-carboxylic acid  97% used for? +

(S)-Boc-5-oxopyrrolidine-2-carboxylic acid  97% is a Boc (tert-butyloxycarbonyl)-protected amino compound for orthogonal synthesis used primarily in the pharmaceutical and peptide synthesis industries. Key applications include solid-phase peptide synthesis (spps) with orthogonal boc/fmoc strategies and amide bond formation via edc/hobt or hatu coupling in peptide synthesis.

Where can I buy (S)-Boc-5-oxopyrrolidine-2-carboxylic acid  97% in the USA? +

ChemContract Research is a trusted USA-based supplier of (S)-Boc-5-oxopyrrolidine-2-carboxylic acid  97%. We offer competitive pricing, fast domestic shipping from our Huntington Beach, California facility, and full quality documentation including Certificates of Analysis (CoA). Request a quote at chemistry@chem-contract.com or call +1 (714) 732-8549.

What purity levels are available for (S)-Boc-5-oxopyrrolidine-2-carboxylic acid  97%? +

ChemContract Research supplies (S)-Boc-5-oxopyrrolidine-2-carboxylic acid  97% in multiple purity grades: ≥95% standard grade, ≥97% high-purity grade, and ≥99% ultra-high-purity grade depending on application requirements. We can also provide custom purity grades through our synthesis capabilities. Contact us for specific purity information and CoA documentation.

Can ChemContract synthesize (S)-Boc-5-oxopyrrolidine-2-carboxylic acid  97% in custom quantities? +

Yes. ChemContract Research offers custom synthesis services for (S)-Boc-5-oxopyrrolidine-2-carboxylic acid  97% from milligram to multi-kilogram scale. Our cGMP-compliant facilities and experienced chemists can accommodate custom specifications, packaging requirements, and delivery timelines. Contact our team to discuss your project.

What is the stereochemical purity of (S)-Boc-5-oxopyrrolidine-2-carboxylic acid  97%? +

ChemContract Research supplies (S)-Boc-5-oxopyrrolidine-2-carboxylic acid  97% with verified enantiomeric or diastereomeric purity as documented in our Certificate of Analysis (CoA). Chiral HPLC analysis is standard for stereodefined compounds. We can provide material with ≥98% ee/de for demanding applications. Contact us for specific optical purity requirements.

How do I remove the Boc group from (S)-Boc-5-oxopyrrolidine-2-carboxylic acid  97%? +

The Boc protecting group in (S)-Boc-5-oxopyrrolidine-2-carboxylic acid  97% is cleanly removed by treatment with trifluoroacetic acid (TFA, 20–50% in DCM) at room temperature, typically within 30–60 minutes. Alternative conditions include HCl in dioxane (4M) or trimethylsilyl triflate with 2,6-lutidine. The Boc group is stable to base, hydrogenation, and many nucleophilic conditions, making it orthogonal to Fmoc and Cbz groups.

How should I store (S)-Boc-5-oxopyrrolidine-2-carboxylic acid  97%? +

Store at room temperature in a sealed container. Stable under neutral and basic conditions; avoid strong acids during storage. Store at room temperature in a tightly sealed container. Protect from moisture and strong bases. Store under recommended conditions. Some chiral compounds may racemize at elevated temperatures or in the presence of base. Always consult the compound-specific Safety Data Sheet (SDS) provided with your order for detailed storage requirements. ChemContract Research includes handling and storage documentation with every shipment.

What is the CAS number of (S)-Boc-5-oxopyrrolidine-2-carboxylic acid  97%? +

The CAS Registry Number for (S)-Boc-5-oxopyrrolidine-2-carboxylic acid  97% is 53100-44-0. This unique identifier is used worldwide to reference this specific compound in chemical databases, regulatory filings, and scientific literature. ChemContract Research supplies this compound with full quality documentation. Contact us at chemistry@chem-contract.com for availability and pricing.

Chemical analysis laboratory with HPLC instruments for purity and impurity testing Custom chemical synthesis reaction setup for pharmaceutical intermediate production

Get (S)-Boc-5-oxopyrrolidine-2-carboxylic acid  97% Delivered This Week

Get competitive pricing, custom quantities, and fast USA delivery. Our chemistry team is standing by to provide specifications, CoA documentation, and a tailored quote for your project.

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