Frequently Asked
Common questions about piperazine-2-carboxylic acid dihydrochloride
What is piperazine-2-carboxylic acid dihydrochloride used for?
piperazine-2-carboxylic acid dihydrochloride is a piperazine-containing compound used extensively as a pharmacokinetic-enhancing motif used primarily in the pharmaceutical and cns therapeutics industries. Key applications include solubility enhancer via piperazine salt formation in drug formulation and amide bond formation via edc/hobt or hatu coupling in peptide synthesis.
Where can I buy piperazine-2-carboxylic acid dihydrochloride in the USA?
ChemContract Research is a trusted USA-based supplier of piperazine-2-carboxylic acid dihydrochloride. We offer competitive pricing, fast domestic shipping from our Huntington Beach, California facility, and full quality documentation including Certificates of Analysis (CoA). Request a quote at chemistry@chem-contract.com or call +1 (714) 732-8549.
What purity levels are available for piperazine-2-carboxylic acid dihydrochloride?
ChemContract Research supplies piperazine-2-carboxylic acid dihydrochloride in multiple purity grades: ≥95% standard grade, ≥97% high-purity grade, and ≥99% ultra-high-purity grade depending on application requirements. We can also provide custom purity grades through our synthesis capabilities. Contact us for specific purity information and CoA documentation.
Can ChemContract synthesize piperazine-2-carboxylic acid dihydrochloride in custom quantities?
Yes. ChemContract Research offers custom synthesis services for piperazine-2-carboxylic acid dihydrochloride from milligram to multi-kilogram scale. Our cGMP-compliant facilities and experienced chemists can accommodate custom specifications, packaging requirements, and delivery timelines. Contact our team to discuss your project.
What coupling reagents work best with piperazine-2-carboxylic acid dihydrochloride?
For amide bond formation from the carboxylic acid in piperazine-2-carboxylic acid dihydrochloride, HATU/DIPEA is recommended for peptide coupling (high yield, low epimerization). EDC/HOBt is a cost-effective alternative for non-peptide amides. T3P (propylphosphonic acid anhydride) offers excellent atom economy with easy workup. For ester formation, DCC/DMAP (Steglich conditions) or Mitsunobu conditions are standard.
Can I get piperazine-2-carboxylic acid dihydrochloride in a different salt form or as the free base?
Yes. ChemContract Research can supply piperazine-2-carboxylic acid dihydrochloride as the free base or convert it to alternative salt forms including hydrochloride, mesylate, tosylate, fumarate, or other pharmaceutically acceptable counter-ions. Salt form selection impacts crystallinity, stability, and solubility — our chemistry team can advise on optimal salt selection for your application. Currently supplied as the Hydrochloride form.
How should I store piperazine-2-carboxylic acid dihydrochloride?
Store at room temperature in a tightly sealed container away from acids. Store at room temperature in a tightly sealed container. Protect from moisture and strong bases. Store at room temperature in a tightly sealed container. Protect from humidity. Always consult the compound-specific Safety Data Sheet (SDS) provided with your order for detailed storage requirements. ChemContract Research includes handling and storage documentation with every shipment.
What is the CAS number of piperazine-2-carboxylic acid dihydrochloride?
The CAS Registry Number for piperazine-2-carboxylic acid dihydrochloride is 3022-15-9. This unique identifier is used worldwide to reference this specific compound in chemical databases, regulatory filings, and scientific literature. ChemContract Research supplies this compound with full quality documentation. Contact us at chemistry@chem-contract.com for availability and pricing.
