Frequently Asked
Common questions about N-BOC-CIS-4-HYDROXY-L-PROLINE METHYL ESTER
What is N-BOC-CIS-4-HYDROXY-L-PROLINE METHYL ESTER used for?
N-BOC-CIS-4-HYDROXY-L-PROLINE METHYL ESTER is a Boc (tert-butyloxycarbonyl)-protected amino compound for orthogonal synthesis used primarily in the pharmaceutical and peptide synthesis industries. Key applications include solid-phase peptide synthesis (spps) with orthogonal boc/fmoc strategies and prodrug development to mask carboxylic acids and improve membrane permeability.
Where can I buy N-BOC-CIS-4-HYDROXY-L-PROLINE METHYL ESTER in the USA?
ChemContract Research is a trusted USA-based supplier of N-BOC-CIS-4-HYDROXY-L-PROLINE METHYL ESTER. We offer competitive pricing, fast domestic shipping from our Huntington Beach, California facility, and full quality documentation including Certificates of Analysis (CoA). Request a quote at chemistry@chem-contract.com or call +1 (714) 732-8549.
What purity levels are available for N-BOC-CIS-4-HYDROXY-L-PROLINE METHYL ESTER?
ChemContract Research supplies N-BOC-CIS-4-HYDROXY-L-PROLINE METHYL ESTER in multiple purity grades: ≥95% standard grade, ≥97% high-purity grade, and ≥99% ultra-high-purity grade depending on application requirements. We can also provide custom purity grades through our synthesis capabilities. Contact us for specific purity information and CoA documentation.
Can ChemContract synthesize N-BOC-CIS-4-HYDROXY-L-PROLINE METHYL ESTER in custom quantities?
Yes. ChemContract Research offers custom synthesis services for N-BOC-CIS-4-HYDROXY-L-PROLINE METHYL ESTER from milligram to multi-kilogram scale. Our cGMP-compliant facilities and experienced chemists can accommodate custom specifications, packaging requirements, and delivery timelines. Contact our team to discuss your project.
How do I remove the Boc group from N-BOC-CIS-4-HYDROXY-L-PROLINE METHYL ESTER?
The Boc protecting group in N-BOC-CIS-4-HYDROXY-L-PROLINE METHYL ESTER is cleanly removed by treatment with trifluoroacetic acid (TFA, 20–50% in DCM) at room temperature, typically within 30–60 minutes. Alternative conditions include HCl in dioxane (4M) or trimethylsilyl triflate with 2,6-lutidine. The Boc group is stable to base, hydrogenation, and many nucleophilic conditions, making it orthogonal to Fmoc and Cbz groups.
What is the stereochemical purity of N-BOC-CIS-4-HYDROXY-L-PROLINE METHYL ESTER?
ChemContract Research supplies N-BOC-CIS-4-HYDROXY-L-PROLINE METHYL ESTER with verified enantiomeric or diastereomeric purity as documented in our Certificate of Analysis (CoA). Chiral HPLC analysis is standard for stereodefined compounds. We can provide material with ≥98% ee/de for demanding applications. Contact us for specific optical purity requirements.
How should I store N-BOC-CIS-4-HYDROXY-L-PROLINE METHYL ESTER?
Store at room temperature in a sealed container. Stable under neutral and basic conditions; avoid strong acids during storage. Store at room temperature in a tightly sealed container away from heat and open flame. Store at room temperature in a tightly sealed container away from heat sources and oxidizers. Store under recommended conditions. Some chiral compounds may racemize at elevated temperatures or in the presence of base. Always consult the compound-specific Safety Data Sheet (SDS) provided with your order for detailed storage requirements. ChemContract Research includes handling and storage documentation with every shipment.
What is the CAS number of N-BOC-CIS-4-HYDROXY-L-PROLINE METHYL ESTER?
The CAS Registry Number for N-BOC-CIS-4-HYDROXY-L-PROLINE METHYL ESTER is 102195-79-9. This unique identifier is used worldwide to reference this specific compound in chemical databases, regulatory filings, and scientific literature. ChemContract Research supplies this compound with full quality documentation. Contact us at chemistry@chem-contract.com for availability and pricing.
