CAS 217806-26-3 · Amine · 3 functional traits · cGMP compliant · Ships from USA in 2-3 days
3-N-Boc-aminoazetidine hydrochloride, 97% (CAS Number: 217806-26-3) is an amine-functionalized compound with nucleophilic nitrogen reactivity featuring a Azetidine ring. ChemContract Research supplies this moderate-complexity compound in high purity from our Huntington Beach, California facility, ensuring consistent quality and reliable domestic delivery throughout the United States. Supplied as the hydrochloride salt form for enhanced stability and handling.
Amines are among the most prevalent functional groups in drug molecules — over 80% of small-molecule pharmaceuticals contain at least one amine moiety. The Boc group is removed cleanly with TFA or HCl in dioxane, making it orthogonal to Fmoc, Cbz, and Alloc protecting groups — essential for synthesizing complex peptide therapeutics. Hydrochloride is the most common salt form for basic drug substances — approximately half of all salt-form drugs on the market are HCl salts, valued for their crystallinity and aqueous solubility.
Primary applications include buchwald–hartwig amination for aryl c–n bond construction and solid-phase peptide synthesis (spps) with orthogonal boc/fmoc strategies. This compound serves researchers and manufacturers across the pharmaceutical, polymer, agrochemical sectors. Whether you require 3-N-Boc-aminoazetidine hydrochloride, 97% for early-stage research, process development, or commercial-scale production, ChemContract Research offers flexible ordering from milligram to multi-kilogram quantities with custom synthesis options and full batch documentation including Certificates of Analysis (CoA) and Safety Data Sheets.
How 3-N-Boc-aminoazetidine hydrochloride, 97% is used across pharmaceutical and polymer sectors
Buchwald–Hartwig amination for aryl C–N bond construction
Solid-phase peptide synthesis (SPPS) with orthogonal Boc/Fmoc strategies
Improved handling characteristics versus the free base form
Reductive amination with aldehydes and ketones for secondary amine synthesis
Multi-step pharmaceutical synthesis requiring selective amine deprotection
Direct formulation excipient in oral solid dosage forms
Detailed specifications for this amine, including purity, molecular weight, and analytical data are available upon request. Every batch from ChemContract Research includes:
Amines may have strong odors and can be corrosive to skin. Handle under adequate ventilation with chemical-resistant gloves and eye protection. Boc-protected compounds are generally stable. TFA deprotection generates isobutylene gas — perform in a fume hood. Handle with standard precautions. Hydrochloride salts are generally more stable than free bases.
Store in a cool, well-ventilated area away from acids and oxidizing agents. Keep containers tightly sealed as many amines are hygroscopic. Store at room temperature in a sealed container. Stable under neutral and basic conditions; avoid strong acids during storage. Store at room temperature in a tightly sealed container. Protect from humidity.
Amines are the most prevalent pharmacophore in drug molecules. 3-N-Boc-aminoazetidine hydrochloride, 97% is supplied with salt-form options and free-base conversion protocols.
Every batch of 3-N-Boc-aminoazetidine hydrochloride, 97% is produced under cGMP conditions with full CoA documentation, HPLC purity verification, and lot traceability.
Ship from our Huntington Beach, CA facility with 2-3 business day domestic delivery. No import delays, no customs fees, no tariff surprises.
Need a specific grade, quantity, or derivative of 3-N-Boc-aminoazetidine hydrochloride, 97%? Our team of PhD chemists can develop custom synthesis solutions for your exact requirements.
Common questions about 3-N-Boc-aminoazetidine hydrochloride, 97%
3-N-Boc-aminoazetidine hydrochloride, 97% is an amine-functionalized compound with nucleophilic nitrogen reactivity used primarily in the pharmaceutical and polymer industries. Key applications include buchwald–hartwig amination for aryl c–n bond construction and solid-phase peptide synthesis (spps) with orthogonal boc/fmoc strategies.
ChemContract Research is a trusted USA-based supplier of 3-N-Boc-aminoazetidine hydrochloride, 97%. We offer competitive pricing, fast domestic shipping from our Huntington Beach, California facility, and full quality documentation including Certificates of Analysis (CoA). Request a quote at chemistry@chem-contract.com or call +1 (714) 732-8549.
ChemContract Research supplies 3-N-Boc-aminoazetidine hydrochloride, 97% in multiple purity grades: ≥95% standard grade, ≥97% high-purity grade, and ≥99% ultra-high-purity grade depending on application requirements. We can also provide custom purity grades through our synthesis capabilities. Contact us for specific purity information and CoA documentation.
Yes. ChemContract Research offers custom synthesis services for 3-N-Boc-aminoazetidine hydrochloride, 97% from milligram to multi-kilogram scale. Our cGMP-compliant facilities and experienced chemists can accommodate custom specifications, packaging requirements, and delivery timelines. Contact our team to discuss your project.
Yes. ChemContract Research can supply 3-N-Boc-aminoazetidine hydrochloride, 97% as the free base or convert it to alternative salt forms including hydrochloride, mesylate, tosylate, fumarate, or other pharmaceutically acceptable counter-ions. Salt form selection impacts crystallinity, stability, and solubility — our chemistry team can advise on optimal salt selection for your application. Currently supplied as the Hydrochloride form.
The amine functionality in 3-N-Boc-aminoazetidine hydrochloride, 97% enables diverse transformations: reductive amination with aldehydes/ketones, acylation to form amides, sulfonylation to form sulfonamides, Buchwald–Hartwig coupling with aryl halides, urea and carbamate formation, and salt generation for improved drug properties. The nucleophilicity of the nitrogen makes it one of the most versatile handles in synthetic chemistry.
Store in a cool, well-ventilated area away from acids and oxidizing agents. Keep containers tightly sealed as many amines are hygroscopic. Store at room temperature in a sealed container. Stable under neutral and basic conditions; avoid strong acids during storage. Store at room temperature in a tightly sealed container. Protect from humidity. Always consult the compound-specific Safety Data Sheet (SDS) provided with your order for detailed storage requirements. ChemContract Research includes handling and storage documentation with every shipment.
The CAS Registry Number for 3-N-Boc-aminoazetidine hydrochloride, 97% is 217806-26-3. This unique identifier is used worldwide to reference this specific compound in chemical databases, regulatory filings, and scientific literature. ChemContract Research supplies this compound with full quality documentation. Contact us at chemistry@chem-contract.com for availability and pricing.
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