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3-Hydroxypiperidine hydrochloride

CAS 64051-79-2 · Piperidine · 3 functional traits · cGMP compliant · Ships from USA in 2-3 days

Piperidine

3-Hydroxypiperidine hydrochloride

Piperidines PharmaceuticalCNS TherapeuticsMedicinal ChemistryResearchFine ChemicalFormulation
CAS Number 64051-79-2
Category Piperidine · Alcohol / Hydroxyl Compound
Origin USA
Compliance cGMP

Questions? Contact our chemistry team:

chemistry@chem-contract.com | +1 (714) 732-8549
In stock — typically ships within 2-3 business days

About 3-Hydroxypiperidine hydrochloride

3-Hydroxypiperidine hydrochloride (CAS Number: 64051-79-2) is a piperidine-containing compound — one of the most drug-prevalent saturated N-heterocycles featuring a Piperidine ring. ChemContract Research supplies this moderate-complexity compound in high purity from our Huntington Beach, California facility, ensuring consistent quality and reliable domestic delivery throughout the United States. Supplied as the hydrochloride salt form for enhanced stability and handling.

The piperidine ring is the most common nitrogen heterocycle in FDA-approved drugs, appearing in over 70 marketed pharmaceuticals across CNS, cardiovascular, and oncology indications. Hydroxyl groups are critical pharmacophores — they serve as hydrogen-bond donors and acceptors, influencing drug–target binding, aqueous solubility, and metabolic susceptibility. Hydrochloride is the most common salt form for basic drug substances — approximately half of all salt-form drugs on the market are HCl salts, valued for their crystallinity and aqueous solubility.

Primary applications include cns drug scaffold (present in donepezil, methylphenidate, fentanyl class) and mitsunobu reaction substrate for stereospecific inversion at chiral centers. This compound serves researchers and manufacturers across the pharmaceutical, cns therapeutics, medicinal chemistry sectors. Whether you require 3-Hydroxypiperidine hydrochloride for early-stage research, process development, or commercial-scale production, ChemContract Research offers flexible ordering from milligram to multi-kilogram quantities with custom synthesis options and full batch documentation including Certificates of Analysis (CoA) and Safety Data Sheets.

Ring Systems: Piperidine
Functional Groups: Hydroxyl (–OH)Chlorine (C–Cl)
Salt Form: Hydrochloride

Piperidine Applications & Target Industries

How 3-Hydroxypiperidine hydrochloride is used across pharmaceutical and cns therapeutics sectors

01

CNS drug scaffold (present in donepezil, methylphenidate, fentanyl class)

02

Mitsunobu reaction substrate for stereospecific inversion at chiral centers

03

Improved handling characteristics versus the free base form

04

Conformationally-restricted amine for receptor binding optimization

05

Oxidation to aldehydes (Swern, Dess–Martin) or ketones for downstream chemistry

06

Direct formulation excipient in oral solid dosage forms

Target Industries: PharmaceuticalCNS TherapeuticsMedicinal ChemistryResearchFine ChemicalFormulation

3-Hydroxypiperidine hydrochloride Specifications

Detailed specifications for this piperidine, including purity, molecular weight, and analytical data are available upon request. Every batch from ChemContract Research includes:

  • Certificate of Analysis (CoA) with purity verification
  • HPLC, NMR, and/or mass spectrometry characterization data
  • Material Safety Data Sheet (MSDS/SDS)
  • Batch-specific documentation and lot traceability
  • Custom analytical testing available on request
Request Full Specifications

Quick Reference

Compound Name 3-Hydroxypiperidine hydrochloride
Type Piperidine
Category Piperidine · Alcohol / Hydroxyl Compound
Purity ≥95% (custom grades available)
Salt Form Hydrochloride
Complexity Moderate (2 functional groups, 1 ring)
Compliance cGMP
Packaging mg to kg scale

Storage & Handling for Piperidines

Handling Guidelines

Handle with standard precautions. Piperidine and some derivatives have strong amine odors. Use a fume hood. Handle with standard precautions. Some alcohols are flammable. Use adequate ventilation and appropriate PPE. Handle with standard precautions. Hydrochloride salts are generally more stable than free bases.

Storage Conditions

Store at room temperature in a well-sealed container. Some N-unsubstituted piperidines are volatile. Store at room temperature in a tightly sealed container away from heat sources and oxidizers. Store at room temperature in a tightly sealed container. Protect from humidity.

Why Buy 3-Hydroxypiperidine hydrochloride From ChemContract?

Quality Assured

Every batch of 3-Hydroxypiperidine hydrochloride is produced under cGMP conditions with full CoA documentation, HPLC purity verification, and lot traceability.

Fast USA Shipping

Ship from our Huntington Beach, CA facility with 2-3 business day domestic delivery. No import delays, no customs fees, no tariff surprises.

Custom Synthesis

Need a specific grade, quantity, or derivative of 3-Hydroxypiperidine hydrochloride? Our team of PhD chemists can develop custom synthesis solutions for your exact requirements.

Frequently Asked

Common questions about 3-Hydroxypiperidine hydrochloride

What is 3-Hydroxypiperidine hydrochloride used for? +

3-Hydroxypiperidine hydrochloride is a piperidine-containing compound — one of the most drug-prevalent saturated N-heterocycles used primarily in the pharmaceutical and cns therapeutics industries. Key applications include cns drug scaffold (present in donepezil, methylphenidate, fentanyl class) and mitsunobu reaction substrate for stereospecific inversion at chiral centers.

Where can I buy 3-Hydroxypiperidine hydrochloride in the USA? +

ChemContract Research is a trusted USA-based supplier of 3-Hydroxypiperidine hydrochloride. We offer competitive pricing, fast domestic shipping from our Huntington Beach, California facility, and full quality documentation including Certificates of Analysis (CoA). Request a quote at chemistry@chem-contract.com or call +1 (714) 732-8549.

What purity levels are available for 3-Hydroxypiperidine hydrochloride? +

ChemContract Research supplies 3-Hydroxypiperidine hydrochloride in multiple purity grades: ≥95% standard grade, ≥97% high-purity grade, and ≥99% ultra-high-purity grade depending on application requirements. We can also provide custom purity grades through our synthesis capabilities. Contact us for specific purity information and CoA documentation.

Can ChemContract synthesize 3-Hydroxypiperidine hydrochloride in custom quantities? +

Yes. ChemContract Research offers custom synthesis services for 3-Hydroxypiperidine hydrochloride from milligram to multi-kilogram scale. Our cGMP-compliant facilities and experienced chemists can accommodate custom specifications, packaging requirements, and delivery timelines. Contact our team to discuss your project.

Can I get 3-Hydroxypiperidine hydrochloride in a different salt form or as the free base? +

Yes. ChemContract Research can supply 3-Hydroxypiperidine hydrochloride as the free base or convert it to alternative salt forms including hydrochloride, mesylate, tosylate, fumarate, or other pharmaceutically acceptable counter-ions. Salt form selection impacts crystallinity, stability, and solubility — our chemistry team can advise on optimal salt selection for your application. Currently supplied as the Hydrochloride form.

What drug discovery applications use 3-Hydroxypiperidine hydrochloride? +

The Piperidine ring system(s) in 3-Hydroxypiperidine hydrochloride is a privileged structure in medicinal chemistry, appearing in numerous FDA-approved drugs. This scaffold is commonly used in kinase inhibitor design, GPCR modulator development, and lead optimization programs. ChemContract supplies this building block for early-stage discovery through process-scale manufacturing.

How should I store 3-Hydroxypiperidine hydrochloride? +

Store at room temperature in a well-sealed container. Some N-unsubstituted piperidines are volatile. Store at room temperature in a tightly sealed container away from heat sources and oxidizers. Store at room temperature in a tightly sealed container. Protect from humidity. Always consult the compound-specific Safety Data Sheet (SDS) provided with your order for detailed storage requirements. ChemContract Research includes handling and storage documentation with every shipment.

What is the CAS number of 3-Hydroxypiperidine hydrochloride? +

The CAS Registry Number for 3-Hydroxypiperidine hydrochloride is 64051-79-2. This unique identifier is used worldwide to reference this specific compound in chemical databases, regulatory filings, and scientific literature. ChemContract Research supplies this compound with full quality documentation. Contact us at chemistry@chem-contract.com for availability and pricing.

Chemical analysis laboratory with HPLC instruments for purity and impurity testing Custom chemical synthesis reaction setup for pharmaceutical intermediate production

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Get competitive pricing, custom quantities, and fast USA delivery. Our chemistry team is standing by to provide specifications, CoA documentation, and a tailored quote for your project.

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