CAS 583823-94-3 · Amine · 3 functional traits · cGMP compliant · Ships from USA in 2-3 days
3-Amino-3-methylbutanoic acid hydrochloride (CAS Number: 583823-94-3) is an amine-functionalized compound with nucleophilic nitrogen reactivity. ChemContract Research supplies this moderate-complexity compound in high purity from our Huntington Beach, California facility, ensuring consistent quality and reliable domestic delivery throughout the United States. Supplied as the hydrochloride salt form for enhanced stability and handling.
Amines are among the most prevalent functional groups in drug molecules — over 80% of small-molecule pharmaceuticals contain at least one amine moiety. Carboxylic acids are among the most synthetically versatile functional groups — they can be converted to amides, esters, acid chlorides, anhydrides, alcohols, and aldehydes in a single step. Hydrochloride is the most common salt form for basic drug substances — approximately half of all salt-form drugs on the market are HCl salts, valued for their crystallinity and aqueous solubility.
Primary applications include buchwald–hartwig amination for aryl c–n bond construction and amide bond formation via edc/hobt or hatu coupling in peptide synthesis. This compound serves researchers and manufacturers across the pharmaceutical, polymer, agrochemical sectors. Whether you require 3-Amino-3-methylbutanoic acid hydrochloride for early-stage research, process development, or commercial-scale production, ChemContract Research offers flexible ordering from milligram to multi-kilogram quantities with custom synthesis options and full batch documentation including Certificates of Analysis (CoA) and Safety Data Sheets.
How 3-Amino-3-methylbutanoic acid hydrochloride is used across pharmaceutical and polymer sectors
Buchwald–Hartwig amination for aryl C–N bond construction
Amide bond formation via EDC/HOBt or HATU coupling in peptide synthesis
Improved handling characteristics versus the free base form
Reductive amination with aldehydes and ketones for secondary amine synthesis
Salt formation with amines to improve drug crystallinity and stability
Direct formulation excipient in oral solid dosage forms
Detailed specifications for this amine, including purity, molecular weight, and analytical data are available upon request. Every batch from ChemContract Research includes:
Amines may have strong odors and can be corrosive to skin. Handle under adequate ventilation with chemical-resistant gloves and eye protection. Acids may be corrosive or irritating. Handle with chemical-resistant gloves and eye protection. Use a fume hood for volatile acids. Handle with standard precautions. Hydrochloride salts are generally more stable than free bases.
Store in a cool, well-ventilated area away from acids and oxidizing agents. Keep containers tightly sealed as many amines are hygroscopic. Store at room temperature in a tightly sealed container. Protect from moisture and strong bases. Store at room temperature in a tightly sealed container. Protect from humidity.
Amines are the most prevalent pharmacophore in drug molecules. 3-Amino-3-methylbutanoic acid hydrochloride is supplied with salt-form options and free-base conversion protocols.
Every batch of 3-Amino-3-methylbutanoic acid hydrochloride is produced under cGMP conditions with full CoA documentation, HPLC purity verification, and lot traceability.
Ship from our Huntington Beach, CA facility with 2-3 business day domestic delivery. No import delays, no customs fees, no tariff surprises.
Need a specific grade, quantity, or derivative of 3-Amino-3-methylbutanoic acid hydrochloride? Our team of PhD chemists can develop custom synthesis solutions for your exact requirements.
Common questions about 3-Amino-3-methylbutanoic acid hydrochloride
3-Amino-3-methylbutanoic acid hydrochloride is an amine-functionalized compound with nucleophilic nitrogen reactivity used primarily in the pharmaceutical and polymer industries. Key applications include buchwald–hartwig amination for aryl c–n bond construction and amide bond formation via edc/hobt or hatu coupling in peptide synthesis.
ChemContract Research is a trusted USA-based supplier of 3-Amino-3-methylbutanoic acid hydrochloride. We offer competitive pricing, fast domestic shipping from our Huntington Beach, California facility, and full quality documentation including Certificates of Analysis (CoA). Request a quote at chemistry@chem-contract.com or call +1 (714) 732-8549.
ChemContract Research supplies 3-Amino-3-methylbutanoic acid hydrochloride in multiple purity grades: ≥95% standard grade, ≥97% high-purity grade, and ≥99% ultra-high-purity grade depending on application requirements. We can also provide custom purity grades through our synthesis capabilities. Contact us for specific purity information and CoA documentation.
Yes. ChemContract Research offers custom synthesis services for 3-Amino-3-methylbutanoic acid hydrochloride from milligram to multi-kilogram scale. Our cGMP-compliant facilities and experienced chemists can accommodate custom specifications, packaging requirements, and delivery timelines. Contact our team to discuss your project.
For amide bond formation from the carboxylic acid in 3-Amino-3-methylbutanoic acid hydrochloride, HATU/DIPEA is recommended for peptide coupling (high yield, low epimerization). EDC/HOBt is a cost-effective alternative for non-peptide amides. T3P (propylphosphonic acid anhydride) offers excellent atom economy with easy workup. For ester formation, DCC/DMAP (Steglich conditions) or Mitsunobu conditions are standard.
Yes. ChemContract Research can supply 3-Amino-3-methylbutanoic acid hydrochloride as the free base or convert it to alternative salt forms including hydrochloride, mesylate, tosylate, fumarate, or other pharmaceutically acceptable counter-ions. Salt form selection impacts crystallinity, stability, and solubility — our chemistry team can advise on optimal salt selection for your application. Currently supplied as the Hydrochloride form.
Store in a cool, well-ventilated area away from acids and oxidizing agents. Keep containers tightly sealed as many amines are hygroscopic. Store at room temperature in a tightly sealed container. Protect from moisture and strong bases. Store at room temperature in a tightly sealed container. Protect from humidity. Always consult the compound-specific Safety Data Sheet (SDS) provided with your order for detailed storage requirements. ChemContract Research includes handling and storage documentation with every shipment.
The CAS Registry Number for 3-Amino-3-methylbutanoic acid hydrochloride is 583823-94-3. This unique identifier is used worldwide to reference this specific compound in chemical databases, regulatory filings, and scientific literature. ChemContract Research supplies this compound with full quality documentation. Contact us at chemistry@chem-contract.com for availability and pricing.
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