Frequently Asked
Common questions about 1-(tert-butoxycarbonyl)-1H-pyrrol-2-ylboronic acid
What is 1-(tert-butoxycarbonyl)-1H-pyrrol-2-ylboronic acid used for?
1-(tert-butoxycarbonyl)-1H-pyrrol-2-ylboronic acid is a boronic acid derivative valued for its role in carbon–carbon bond-forming reactions used primarily in the pharmaceutical and medicinal chemistry industries. Key applications include suzuki–miyaura cross-coupling for biaryl and heterobiaryl synthesis and solid-phase peptide synthesis (spps) with orthogonal boc/fmoc strategies.
Where can I buy 1-(tert-butoxycarbonyl)-1H-pyrrol-2-ylboronic acid in the USA?
ChemContract Research is a trusted USA-based supplier of 1-(tert-butoxycarbonyl)-1H-pyrrol-2-ylboronic acid. We offer competitive pricing, fast domestic shipping from our Huntington Beach, California facility, and full quality documentation including Certificates of Analysis (CoA). Request a quote at chemistry@chem-contract.com or call +1 (714) 732-8549.
What purity levels are available for 1-(tert-butoxycarbonyl)-1H-pyrrol-2-ylboronic acid?
ChemContract Research supplies 1-(tert-butoxycarbonyl)-1H-pyrrol-2-ylboronic acid in multiple purity grades: ≥95% standard grade, ≥97% high-purity grade, and ≥99% ultra-high-purity grade depending on application requirements. We can also provide custom purity grades through our synthesis capabilities. Contact us for specific purity information and CoA documentation.
Can ChemContract synthesize 1-(tert-butoxycarbonyl)-1H-pyrrol-2-ylboronic acid in custom quantities?
Yes. ChemContract Research offers custom synthesis services for 1-(tert-butoxycarbonyl)-1H-pyrrol-2-ylboronic acid from milligram to multi-kilogram scale. Our cGMP-compliant facilities and experienced chemists can accommodate custom specifications, packaging requirements, and delivery timelines. Contact our team to discuss your project.
How do I remove the Boc group from 1-(tert-butoxycarbonyl)-1H-pyrrol-2-ylboronic acid?
The Boc protecting group in 1-(tert-butoxycarbonyl)-1H-pyrrol-2-ylboronic acid is cleanly removed by treatment with trifluoroacetic acid (TFA, 20–50% in DCM) at room temperature, typically within 30–60 minutes. Alternative conditions include HCl in dioxane (4M) or trimethylsilyl triflate with 2,6-lutidine. The Boc group is stable to base, hydrogenation, and many nucleophilic conditions, making it orthogonal to Fmoc and Cbz groups.
What is the stereochemical purity of 1-(tert-butoxycarbonyl)-1H-pyrrol-2-ylboronic acid?
ChemContract Research supplies 1-(tert-butoxycarbonyl)-1H-pyrrol-2-ylboronic acid with verified enantiomeric or diastereomeric purity as documented in our Certificate of Analysis (CoA). Chiral HPLC analysis is standard for stereodefined compounds. We can provide material with ≥98% ee/de for demanding applications. Contact us for specific optical purity requirements.
How should I store 1-(tert-butoxycarbonyl)-1H-pyrrol-2-ylboronic acid?
Store in a tightly sealed container at room temperature under dry conditions. Protect from prolonged moisture exposure. Store at room temperature in a sealed container. Stable under neutral and basic conditions; avoid strong acids during storage. Store under recommended conditions. Some chiral compounds may racemize at elevated temperatures or in the presence of base. Always consult the compound-specific Safety Data Sheet (SDS) provided with your order for detailed storage requirements. ChemContract Research includes handling and storage documentation with every shipment.
What is the CAS number of 1-(tert-butoxycarbonyl)-1H-pyrrol-2-ylboronic acid?
The CAS Registry Number for 1-(tert-butoxycarbonyl)-1H-pyrrol-2-ylboronic acid is 135884-31-0. This unique identifier is used worldwide to reference this specific compound in chemical databases, regulatory filings, and scientific literature. ChemContract Research supplies this compound with full quality documentation. Contact us at chemistry@chem-contract.com for availability and pricing.
