CAS 137076-22-3 · Aldehyde · 4 functional traits · cGMP compliant · Ships from USA in 2-3 days
1-Piperidinecarboxylic acid, 4-formyl-, 1,1-dimethylethylester (CAS Number: 137076-22-3) is an aldehyde with a highly electrophilic carbonyl group featuring a Piperidine ring with defined stereochemistry. ChemContract Research supplies this moderate-complexity compound in high purity from our Huntington Beach, California facility, ensuring consistent quality and reliable domestic delivery throughout the United States.
The aldehyde carbonyl is one of the most reactive electrophilic centers in organic chemistry, enabling diverse transformations from imine formation to asymmetric allylation. The piperidine ring is the most common nitrogen heterocycle in FDA-approved drugs, appearing in over 70 marketed pharmaceuticals across CNS, cardiovascular, and oncology indications. Carboxylic acids are among the most synthetically versatile functional groups — they can be converted to amides, esters, acid chlorides, anhydrides, alcohols, and aldehydes in a single step.
Primary applications include reductive amination for c–n bond formation in api synthesis and cns drug scaffold (present in donepezil, methylphenidate, fentanyl class). This compound serves researchers and manufacturers across the pharmaceutical, fragrance & flavor, fine chemical sectors. Whether you require 1-Piperidinecarboxylic acid, 4-formyl-, 1,1-dimethylethylester for early-stage research, process development, or commercial-scale production, ChemContract Research offers flexible ordering from milligram to multi-kilogram quantities with custom synthesis options and full batch documentation including Certificates of Analysis (CoA) and Safety Data Sheets.
How 1-Piperidinecarboxylic acid, 4-formyl-, 1,1-dimethylethylester is used across pharmaceutical and fragrance & flavor sectors
Reductive amination for C–N bond formation in API synthesis
CNS drug scaffold (present in donepezil, methylphenidate, fentanyl class)
Amide bond formation via EDC/HOBt or HATU coupling in peptide synthesis
Enantiopure building block for single-enantiomer drug development
Wittig and Horner–Wadsworth–Emmons olefination substrates
Conformationally-restricted amine for receptor binding optimization
Detailed specifications for this aldehyde, including purity, molecular weight, and analytical data are available upon request. Every batch from ChemContract Research includes:
Aldehydes can be irritating to skin, eyes, and respiratory tract. Handle in a well-ventilated fume hood. Many are volatile and flammable. Handle with standard precautions. Piperidine and some derivatives have strong amine odors. Use a fume hood. Acids may be corrosive or irritating. Handle with chemical-resistant gloves and eye protection. Use a fume hood for volatile acids. Handle with standard precautions. Ensure proper labeling of stereochemical identity to prevent mix-ups.
Store at recommended temperature under inert atmosphere. Protect from air to prevent oxidation to the corresponding carboxylic acid. Store at room temperature in a well-sealed container. Some N-unsubstituted piperidines are volatile. Store at room temperature in a tightly sealed container. Protect from moisture and strong bases. Store under recommended conditions. Some chiral compounds may racemize at elevated temperatures or in the presence of base.
Every batch of 1-Piperidinecarboxylic acid, 4-formyl-, 1,1-dimethylethylester is produced under cGMP conditions with full CoA documentation, HPLC purity verification, and lot traceability.
Ship from our Huntington Beach, CA facility with 2-3 business day domestic delivery. No import delays, no customs fees, no tariff surprises.
Need a specific grade, quantity, or derivative of 1-Piperidinecarboxylic acid, 4-formyl-, 1,1-dimethylethylester? Our team of PhD chemists can develop custom synthesis solutions for your exact requirements.
Common questions about 1-Piperidinecarboxylic acid, 4-formyl-, 1,1-dimethylethylester
1-Piperidinecarboxylic acid, 4-formyl-, 1,1-dimethylethylester is an aldehyde with a highly electrophilic carbonyl group used primarily in the pharmaceutical and fragrance & flavor industries. Key applications include reductive amination for c–n bond formation in api synthesis and cns drug scaffold (present in donepezil, methylphenidate, fentanyl class).
ChemContract Research is a trusted USA-based supplier of 1-Piperidinecarboxylic acid, 4-formyl-, 1,1-dimethylethylester. We offer competitive pricing, fast domestic shipping from our Huntington Beach, California facility, and full quality documentation including Certificates of Analysis (CoA). Request a quote at chemistry@chem-contract.com or call +1 (714) 732-8549.
ChemContract Research supplies 1-Piperidinecarboxylic acid, 4-formyl-, 1,1-dimethylethylester in multiple purity grades: ≥95% standard grade, ≥97% high-purity grade, and ≥99% ultra-high-purity grade depending on application requirements. We can also provide custom purity grades through our synthesis capabilities. Contact us for specific purity information and CoA documentation.
Yes. ChemContract Research offers custom synthesis services for 1-Piperidinecarboxylic acid, 4-formyl-, 1,1-dimethylethylester from milligram to multi-kilogram scale. Our cGMP-compliant facilities and experienced chemists can accommodate custom specifications, packaging requirements, and delivery timelines. Contact our team to discuss your project.
ChemContract Research supplies 1-Piperidinecarboxylic acid, 4-formyl-, 1,1-dimethylethylester with verified enantiomeric or diastereomeric purity as documented in our Certificate of Analysis (CoA). Chiral HPLC analysis is standard for stereodefined compounds. We can provide material with ≥98% ee/de for demanding applications. Contact us for specific optical purity requirements.
The Piperidine ring system(s) in 1-Piperidinecarboxylic acid, 4-formyl-, 1,1-dimethylethylester is a privileged structure in medicinal chemistry, appearing in numerous FDA-approved drugs. This scaffold is commonly used in kinase inhibitor design, GPCR modulator development, and lead optimization programs. ChemContract supplies this building block for early-stage discovery through process-scale manufacturing.
Store at recommended temperature under inert atmosphere. Protect from air to prevent oxidation to the corresponding carboxylic acid. Store at room temperature in a well-sealed container. Some N-unsubstituted piperidines are volatile. Store at room temperature in a tightly sealed container. Protect from moisture and strong bases. Store under recommended conditions. Some chiral compounds may racemize at elevated temperatures or in the presence of base. Always consult the compound-specific Safety Data Sheet (SDS) provided with your order for detailed storage requirements. ChemContract Research includes handling and storage documentation with every shipment.
The CAS Registry Number for 1-Piperidinecarboxylic acid, 4-formyl-, 1,1-dimethylethylester is 137076-22-3. This unique identifier is used worldwide to reference this specific compound in chemical databases, regulatory filings, and scientific literature. ChemContract Research supplies this compound with full quality documentation. Contact us at chemistry@chem-contract.com for availability and pricing.
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