CAS 55276-43-2 · Sulfur-Containing Compound · 2 functional traits · cGMP compliant · Ships from USA in 2-3 days
1-Methanesulfonylpiperazine (CAS Number: 55276-43-2) is a sulfur-functionalized compound with diverse reactivity featuring a Piperazine ring. ChemContract Research supplies this simple-complexity compound in high purity from our Huntington Beach, California facility, ensuring consistent quality and reliable domestic delivery throughout the United States.
Sulfonamides are one of the oldest and most successful pharmacophores in medicinal chemistry — present in antibiotics, diuretics, COX-2 inhibitors, and HIV protease inhibitors. The two nitrogen atoms of piperazine provide both a basic amine (pKa ~9.8) for salt formation and a secondary amine (pKa ~5.3) for functionalization, giving medicinal chemists dual synthetic handles.
Primary applications include sulfonamide pharmacophore installation for antibiotic and diuretic development and solubility enhancer via piperazine salt formation in drug formulation. This compound serves researchers and manufacturers across the pharmaceutical, medicinal chemistry, agrochemical sectors. Whether you require 1-Methanesulfonylpiperazine for early-stage research, process development, or commercial-scale production, ChemContract Research offers flexible ordering from milligram to multi-kilogram quantities with custom synthesis options and full batch documentation including Certificates of Analysis (CoA) and Safety Data Sheets.
How 1-Methanesulfonylpiperazine is used across pharmaceutical and medicinal chemistry sectors
Sulfonamide pharmacophore installation for antibiotic and diuretic development
Solubility enhancer via piperazine salt formation in drug formulation
Tosyl and mesyl protecting groups for hydroxyl and amine functionalities
Bioisosteric replacement for piperidine to improve metabolic profile
Triflate leaving group for palladium-catalyzed cross-coupling
Antipsychotic and anxiolytic drug scaffold (aripiprazole class)
Detailed specifications for this sulfur-containing compound, including purity, molecular weight, and analytical data are available upon request. Every batch from ChemContract Research includes:
Some sulfur compounds have strong odors. Handle in a well-ventilated fume hood. Consult the SDS for compound-specific hazards. Handle with standard precautions. Some piperazine derivatives may be irritating. Use adequate ventilation.
Store in a cool, dry place in a tightly sealed container. Protect from moisture and light as specified. Store at room temperature in a tightly sealed container away from acids.
Every batch of 1-Methanesulfonylpiperazine is produced under cGMP conditions with full CoA documentation, HPLC purity verification, and lot traceability.
Ship from our Huntington Beach, CA facility with 2-3 business day domestic delivery. No import delays, no customs fees, no tariff surprises.
Need a specific grade, quantity, or derivative of 1-Methanesulfonylpiperazine? Our team of PhD chemists can develop custom synthesis solutions for your exact requirements.
Common questions about 1-Methanesulfonylpiperazine
1-Methanesulfonylpiperazine is a sulfur-functionalized compound with diverse reactivity used primarily in the pharmaceutical and medicinal chemistry industries. Key applications include sulfonamide pharmacophore installation for antibiotic and diuretic development and solubility enhancer via piperazine salt formation in drug formulation.
ChemContract Research is a trusted USA-based supplier of 1-Methanesulfonylpiperazine. We offer competitive pricing, fast domestic shipping from our Huntington Beach, California facility, and full quality documentation including Certificates of Analysis (CoA). Request a quote at chemistry@chem-contract.com or call +1 (714) 732-8549.
ChemContract Research supplies 1-Methanesulfonylpiperazine in multiple purity grades: ≥95% standard grade, ≥97% high-purity grade, and ≥99% ultra-high-purity grade depending on application requirements. We can also provide custom purity grades through our synthesis capabilities. Contact us for specific purity information and CoA documentation.
Yes. ChemContract Research offers custom synthesis services for 1-Methanesulfonylpiperazine from milligram to multi-kilogram scale. Our cGMP-compliant facilities and experienced chemists can accommodate custom specifications, packaging requirements, and delivery timelines. Contact our team to discuss your project.
The Piperazine ring system(s) in 1-Methanesulfonylpiperazine is a privileged structure in medicinal chemistry, appearing in numerous FDA-approved drugs. This scaffold is commonly used in kinase inhibitor design, GPCR modulator development, and lead optimization programs. ChemContract supplies this building block for early-stage discovery through process-scale manufacturing.
Store in a cool, dry place in a tightly sealed container. Protect from moisture and light as specified. Store at room temperature in a tightly sealed container away from acids. Always consult the compound-specific Safety Data Sheet (SDS) provided with your order for detailed storage requirements. ChemContract Research includes handling and storage documentation with every shipment.
The CAS Registry Number for 1-Methanesulfonylpiperazine is 55276-43-2. This unique identifier is used worldwide to reference this specific compound in chemical databases, regulatory filings, and scientific literature. ChemContract Research supplies this compound with full quality documentation. Contact us at chemistry@chem-contract.com for availability and pricing.
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