1-FMOC-2-PIPERIDINECARBOXYLIC ACID

1-FMOC-2-PIPERIDINECARBOXYLIC ACID is a piperidine-containing compound — one of the most drug-prevalent saturated N-heterocycles used primarily in the pharmaceutical and cns therapeutics industries. Key applications include cns drug scaffold (present in donepezil, methylphenidate, fentanyl class) and amide bond formation via edc/hobt or hatu coupling in peptide synthesis.

ChemContract Research is a trusted USA-based supplier of 1-FMOC-2-PIPERIDINECARBOXYLIC ACID. We offer competitive pricing, fast domestic shipping from our Huntington Beach, California facility, and full quality documentation including Certificates of Analysis (CoA). Request a quote at chemistry@chem-contract.com or call +1 (714) 732-8549.

ChemContract Research supplies 1-FMOC-2-PIPERIDINECARBOXYLIC ACID in multiple purity grades: ≥95% standard grade, ≥97% high-purity grade, and ≥99% ultra-high-purity grade depending on application requirements. We can also provide custom purity grades through our synthesis capabilities. Contact us for specific purity information and CoA documentation.

Yes. ChemContract Research offers custom synthesis services for 1-FMOC-2-PIPERIDINECARBOXYLIC ACID from milligram to multi-kilogram scale. Our cGMP-compliant facilities and experienced chemists can accommodate custom specifications, packaging requirements, and delivery timelines. Contact our team to discuss your project.

For amide bond formation from the carboxylic acid in 1-FMOC-2-PIPERIDINECARBOXYLIC ACID, HATU/DIPEA is recommended for peptide coupling (high yield, low epimerization). EDC/HOBt is a cost-effective alternative for non-peptide amides. T3P (propylphosphonic acid anhydride) offers excellent atom economy with easy workup. For ester formation, DCC/DMAP (Steglich conditions) or Mitsunobu conditions are standard.

The Piperidine ring system(s) in 1-FMOC-2-PIPERIDINECARBOXYLIC ACID is a privileged structure in medicinal chemistry, appearing in numerous FDA-approved drugs. This scaffold is commonly used in kinase inhibitor design, GPCR modulator development, and lead optimization programs. ChemContract supplies this building block for early-stage discovery through process-scale manufacturing.

Store at room temperature in a well-sealed container. Some N-unsubstituted piperidines are volatile. Store at room temperature in a tightly sealed container. Protect from moisture and strong bases. Always consult the compound-specific Safety Data Sheet (SDS) provided with your order for detailed storage requirements. ChemContract Research includes handling and storage documentation with every shipment.